Elevated Yap and Its Downstream Targets Ccn1 and Ccn2 in Basal Cell Carcinoma

Quan, Taihao; Xu, Yiru; Qin, Zhaoping; Robichaud, Patrick; Betcher, Stephanie; Calderone, Ken; He, Tianyuan; Johnson, Timothy M.; Voorhees, John J.; Fisher, Gary J. (April 2014). "Elevated Yap and Its Downstream Targets Ccn1 and Ccn2 in Basal Cell Carcinoma". 184 (4): 937–943. doi:10.1016/j.ajpath.2013.12.017. ISSN 0002-9440.

Abstract: Document type: Research article focusing on Basal Cell Carcinoma. The work investigates the role of Elevated Yap and its downstream targets Ccn1 and Ccn2 in Basal Cell Carcinoma. The study examines the molecular mechanisms involved in the pathogenesis of Basal Cell Carcinoma, specifically analyzing the interactions between Elevated Yap, Ccn1, and Ccn2. The research includes a detailed exploration of the signaling pathways and genetic factors contributing to tumor development. The article discusses the implications of these findings for understanding the biology of Basal Cell Carcinoma and potential therapeutic targets. The geographic focus is not explicitly stated, but the subject matter is relevant to global cancer research. Specific taxa, ecological systems, or linguistic topics are not mentioned. The work does not provide a historical account or policy review. The time period of the research is not specified. The article is structured to include a comprehensive analysis of the molecular interactions and their relevance to cancer biology. The scope of the document is contained within the study of Basal Cell Carcinoma and its associated molecular pathways.

Extra details:

MAG: 184368635
OpenAlex: W184368635
QID: Q37672884